Thursday, 18th August International Veterinary Immunology Symposium 2016

• Dendritic cell and macrophages subsets: impact for vaccine strategies in large mammals - Isabelle Schwartz
• Immune response of porcine T lymphocytes - Armin Saalmüller
• Variegated expression of members of the WC1 pattern recognition receptor and co-receptor multi-gene family on bovine gamma delta T cells direct their response to pathogens - Cynthia L Baldwin

• The role of nutrition in the regulation of the porcine immune response; the regulatory actions of vitamin A and vitamin D on cell signaling pathways in epithelial cells and macrophages - Harry Dawson
• The anti-inflammatory and anti-fibrotic effects K_ca3.1 ion channel inhibition in sheep models of asthma and pulmonary fibrosis - Louise Organ
• The pig as a large preclinical model for therapeutic human anti-cancer vaccine development - Nana H Overgaard
• Knockdown of p65 subunit of NF-kB transcription factor down-regulates the induction of pro-inflammatory cytokines & chemokine in the lung epithelial cells infected with avian influenza H9N2 virus - Alireza Haghparast
• Characterisation of a Novel Ferret CD3 mAb and Ferret T cell Responses. - Matthew P Bruce

• Immunocompetent animal model to examine influence of immunity on oncolytic virotherapy with a recombinant measles virus - Koichiro Shoji
• Engineering bovine antibodies for development of novel Therapeutics and vaccines - Azad Kaushik
• A new generation of affordable vaccine for prevention of bovine Staphylococcus aureus mastitis - Bror Morein
• Swine plasma immunoglobulins for prevention and treatment of post-weaning diarrhoea: Safety -and preclinical results - Chris J Hedegaard
• WC1 is a Hybrid gammadelta TCR Coreceptor and Pattern Recognition Receptor for Pathogenic Bacteria. - Janice C Telfer

Followed by Jayne Hope and Dirk Werling, will speak on their experiences of veterinary immunology teaching and course organisation.

Teaching Veterinary Immunology panel discussion to follow.  

• Teaching immunology by stealth: Embedding immunology into a new DVM curriculum at the University of Melbourne  - Wayne Kimpton

• Passive Immunotherapy Using Human Immunoglobulin from Transchromosomic Bovine - Eddie Sullivan
• The influence of selected antibiotics on humoral immune response induced by erysipelas vaccination in pigs* - Małgorzata Pomorska-Mól
• Comparative analysis of signature genes in PRRSV-infected porcine monocyte-derived dendritic cells at differential activation statuses. - Laura C Miller
• Genomic structure of porcine NLRC4 and NAIP genes - Hirohide Uenishi
• Interleukin-1 receptor antagonist (IL-1Ra): a potential negative immunomodulatory mediator during an early phase of Porcine Reproductive and Respiratory Syndrome virus (PRRSV) infection - Teerawut Nedumpun
• Chicken IFNλ as an adjuvant for NDV - Daniel S Layton
• Antiviral host responses by swine are limited following influenza-a virus infection - Ralph A Tripp

From 2:55 PM Panel discussion: Future of Veterinary Toolkit Efforts

Panelists: Joan Lunney, USA; Jayne Hope UK; Gregers Jungersen, Denmark; Matt Bruce, Australia

Discussion Points
1) current efforts to produce new reagents; coordination efforts
2) future funding for Immune Toolkit efforts and long term access to reagents (especially those with limited commercial potential)
3) orphan reagents, how to avoid this happening and options
4) validating cross-reactivity, ensuring that specificities are correct through use of well characterized systems and positive controls;
5) sustainability of searchable databases [funding and maintaining them]

• US-UK Collaborative Swine Immune Toolkit Initiative: Development of new immune reagents for swine health, vaccine and disease studies. - Joan Lunney
• Development of cytometric bead array assays to quantify sheep cytokines - Gabriela Simonova
• Monoclonal antibodies for the analysis of bovine CD4+ helper T cell subsets - Tatjana Sitt
• Tracking the elusive cytotoxic T cell response in pigs - Gregers Jungersen

• A second transmissible cancer in Tasmanian devils - Ruth Pye
• Characterisation of CD4⁺ T and CD8⁺ T Cells in healthy and diseased koalas (Phascolarctos cinereus) using cell-type-specific monoclonal antibodies - Chandan Mangar
• Characterisation of bare-nosed wombat immune gene responses to sarcoptic mange - Tamieka Fraser
• Development of monoclonal antibodies as therapeutic tools for tick paralysis - Manuel Rodriguez Valle
• Development of a chlamydial vaccine for koalas - Peter Timms

• From Antibodies to Nanobodies: How a serendipitous discovery led to a major biotech opportunity. - Serge Muyldermans

Location: Gold Coast Convention and Exhibition Centre.